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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '303e88c2de66d8a09715814024c4a86feac74b5a7028af926e8948f37d8ca670' 
  AND token = 'Mn9DKZlAucoy4KN2bqlyVd75asTwEVegS+gWVAH4hZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}