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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8b2fdad790b9ecc961b8ea633b222efc0f6a49784876a5a24e1413de675cad2' 
  AND token = 'gKX+aciYVdArFU+vXpdkBPN5mUbEcifHZtP30uCBHN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}