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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e132a2c407e28a24b764c00e4170f795873d60ce4c177ea7433cac7b29d52ad' 
  AND token = 'yncVPE7WA6pt+fTnvsUgKx7a17y7KNVIn6yIX6zhRhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}