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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3301bfe887227dcd57e925976ba407c15d84e35525bc2ce8294d5c774ce602b0' 
  AND token = '3qMkXkcTJF84dgETCF2dA09l0MgMordouN1ryfuz0M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}