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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff6c163a7ffe3d57c3355c14c730e32f53393d7e9bd5f23f9f19438ba047a5d6' 
  AND token = '+M9Xuqb3FpbDWGSr3TsJx45wR1c0j0NhS8EM+6mPR8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}