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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72b935b443e75f36d3ad298504238b5ef11c62afb1148e3217b6c7a01b67fb08' 
  AND token = 'eqsjTs1IAyJ39khTj8R9F7DTQpWs1rVMY63IeGvksvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}