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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa9a950ff77f08da84d2e7a6b5deaff021ce9cd98bea72aaaca276b6f8ff57f7' 
  AND token = 'RAxgQlsJEQBU/RboTgKxkFlT+wurXixU93xnRhrGcnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}