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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f7e8cbddb64ab51088138f5182cf18faa5a5b0f59f1f048ac4ec9bfb3e01692' 
  AND token = 'Y4gTTwteEYM8i/Sc6aSXEsCzhfUB2oR9Gd2yAqawFb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}