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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7221090c16c88dfe2f0ed9719c25cdc1d8de3c73990c23644b3143c254d9679c' 
  AND token = '7F3jPSgLo9p2HJnKiG2X2Cdf4lB93s3U0y8XvPuDUNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}