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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '263b89ce5e48e621dfd0726adee47176392a5ee895095b08b25a31fcba460f38' 
  AND token = 'jQndDLEJcdBfzIaJfVW1p3HuOoHtEQ/zyT+ztC3Ny+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}