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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '637299fd99b6afc976a8a62c32530c3281c773f728e235cd97f6be87c5a643d0' 
  AND token = 'bVddJ3TB/QLPnCYOTsLK5++4lALrs1fe1/i4YS7MkoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}