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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c659ab2c2eec5d7faac5a1b1e326bc0eb5fa220853c448fe5b08526de5c4b080' 
  AND token = '6GOq14X0ZxFuBoMxFUBL2kso6EjGQUW8SJiGEPItEH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}