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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df40dba5685d6f5267fdb58e30a6ebdae8516a914f7d94a801055bd9bbfd649e' 
  AND token = 'uJOH4xv86eFpPop8km68bXGT9vbCuOechh/EBWr5poo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}