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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72869ee3adff289e3f16751ee489403cc5657f37253a4f7341fde294a6fbe5d7' 
  AND token = 'DvEXdmr/Mjm+yOr9uxOZO6fStWxcaVIp0WScQLAwaAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}