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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e7d19c973a72a1221a585cae2824879a17bf4ebf7dca978b13c2b877714c595' 
  AND token = 'f2U/Sjy33VRNxPwdMUcYk7KJI7m4+/L7MzU3AoPYDAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}