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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69adcc9f2e14fc5d4fcd9f9584d72ada9b94920880dc855406ff7e08fef50f5b' 
  AND token = '14NlAPO/LgBbLM1OrPiCYT8O/LcotmEvHvOaBrtnjm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}