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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5be581653b9f5b15c2d08a65ea5e010e26acb3f89b6e3267ac307d192a731248' 
  AND token = '/ymkdyOnEDWlYZJqOXbNvrsCFydFNYE/c0kb9IpMPuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}