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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a95e0c34a5833ab3ea4372aed4469f278642447703bef873acef40916ff842b' 
  AND token = 'u8vDNz8RRldNZGpfvy3M6o0ttDPlQUkA21hRHCU62U8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}