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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f949fe0fdfcb67a28c7f5634cb9e47463bc9f74b7a0b12c00cd02f43ced71e8' 
  AND token = 'Dx5lnFB+NWTnktGmAOUAq5rZKAv3RSfj2bqx0SQNR14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}