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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2d0a3e30f574b7f0d776c1eeb7bb62f57b053253aa429787ae295053f6edc78' 
  AND token = 'm0MAI9ALP9pn3+TP2TzwFiGuM9SkwBAzuCzrj4XoLYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}