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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c6e742badb2803b05f23c06cc067e2aa57c9ba9de89e08872dde5b3c07e2017' 
  AND token = 'F3X+BS6cco8pvaGTMPPnODAb82pRs6jD9kPq3kVFzcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}