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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '320de04488656ac629a9101e1f4b69c1571c3487452611dfdb30d02bfeab87b7' 
  AND token = 'RYEW9Jv6Ioi1On4VSdEIqgwhrrH/RyYQo1rFPbikWhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}