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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5478bd16b1875deb5d5c0e4e49d0005240055efb3ce88dbe4735463f6dca6506' 
  AND token = 'wA5Wlb6OfVItJ926Z4WrWi7/YDxOjQAccVSDBv0GCZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}