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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e26b9b5faeacaf6f46b6f23b05f26b0e90af8a25b00f94f168f3d7d5553d656' 
  AND token = 's9umY7Mz6cZLyMDWQv6S8v+7lDUvk5jIIslUg+7T51Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}