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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1969728433011c65c055ca038918a74d78cd8bc302b49cadfd07309b429d5ca1' 
  AND token = 'OMf3vivzpKjiAS9oRcamXvh+0eNKDUQoAjIdBCAZAbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}