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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd879ecf1bc85e4061febce9d01fbdeaf98bacf226d4512aa8de6c5d7c48560eb' 
  AND token = 'g0a4B5P0ofg7SBXXdB58osKa2aw2vi+Uddk+ORNvgYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}