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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22dcaae52a4aa95ef4b79eee783db684a7566eea8de32693af78c5b19558fa9' 
  AND token = 'tV+6yjEiZZ+HI7as+VE2mC49ybLc4YDkeNr3tHOxfeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}