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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7419c6244bb375865e62fa4a90ac7c5a0368aa8a12fbd13964a801631e94947' 
  AND token = 'u38wcX5KWLZfQRKKHHB0sET4RA3dNFtw8dGr/iQNJRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}