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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5a6be325c66d7c4f643fa09b2cc673ada63d6268c7742d6a14fed9ec12dfe70' 
  AND token = 'vDGJ7isSAZk7R0faSVEZlx/FwNinNcSEvKAOhyI3U6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}