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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '894e4cdb49ffba221922e1f2d60f868d779d538d39d8fc123843e445b5c2306c' 
  AND token = '+gPX6Xv01pQ2G0dbsIBV72csdiZHpvV1BOiS9W3jmyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}