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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f279a7b3e627fb8418e1555ecbf7bf2534fa7eef062912e34e22cfac72b11b3' 
  AND token = 'f07pkDomp8T/aSHVMpd/CzgLYZeafQ1NZnENL1SN5C0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}