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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c45120f8ab2967780827c977ec70b5314dc37521df2f56693d21a16123935fd' 
  AND token = 'FC9b3CiylWWs0zdBZAK7eG2fGDeTmAa+R4zQxBfgYVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}