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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18f2ffccb628d119111533244d2dbb6c355bb8be93711f8735fb75e32f332247' 
  AND token = '6nCwG5eqa63cNGN1Dnl+8b0vgtgkfDJ+BFJdH+/HSRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}