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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b19b095e5e77c721b1944a1f1b50594d4bdf9fb7e68fa21a86a0100bfbbbf2e' 
  AND token = 'qKRnq2aw0yi6yvABzLFk8FAnbJxgJf1YT1lhOaIGuE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}