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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80bd4324cc64ed5458b30a5ac611c181e945028fed89d0b51089fd0fa1e58dea' 
  AND token = '35N3ET12YXtl8DWVhM+gZyr3ks43GTEEtKG8H3ohFVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}