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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7044ef6d61146c261fa8a09e0f0c087f77ba52724d3d4d07115c9b02533da0ad' 
  AND token = 'LTRJosk+sfeelu4zTm1Be3sGkpSansHqIL0fccrkW/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}