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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddf8c4949d2d53f5190fb7d0603e200c35bd6006f24b5c2d1fd7595be59c5ee6' 
  AND token = 'QioPdyMHoaUoLpuT2fvUloQv6WYJWaFidKEw5mHjhyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}