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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe4aa6176c803ec13d4255eeabb9e67e5af8017d223ec82942a136036baf2fb1' 
  AND token = 'XeH/by9fgTC1r7i1zxAYV/RjQV9PFl884qHkVqkIQnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}