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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654037befc0ab02687e28e26bbea9fd3bfb2f91a21e2a3ae1a3af3ef9f3578c3' 
  AND token = 'rw2vnf3G1S24Tue932MoE30jy/9GW4gTIf9mZvI6iII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}