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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3aaccb96b9dc5e8dcd8f0e384b340ddb8ef69ef057551dc73c934d913289adb1' 
  AND token = 'z94hQKH1S1qL+ZXktYECnB4rKs5j5bCqm1FyhE1Qmaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}