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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2df893fe2dbd681efaf8cbd9bd1a2bb806b0f2fb4fe89a8775290a6d0800c359' 
  AND token = 'WASmn12OW3VFLnEIbN515WEbnSBG4PS2zV/1b638QXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}