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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e14e233fbbda5bb47c36ec3d51578a49f5d2c186b46ef595a4e624a94b5c87e9' 
  AND token = 'NCKCdv3xYcZupU3C1sgv6yXK8Hi7tNPVXMCsKZ2CbLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}