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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10dcf07341569314002ba20e82c00ee0250f78b820546ce78caadf7ffae7a220' 
  AND token = 'HabBawwZTkh5LXdN9u8WzVwfjNVkM+8nIhcc6+e3DLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}