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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4abd542df96dcd8769a7f4ec8e3aa4c9fde15b830b65981d0a75f39326877017' 
  AND token = 'JLd+EWDw/tEmcZe/cTjXADiYTgNzCYV96zzr5MeW0rA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}