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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d7e08a02498e8b3a1f67d494362c4fdcabfdc51cef1fc58a1322b65fd091ea1' 
  AND token = 'OH+Sg1ogwKrDFyxeN8j9pV5N4WGW12Y9SrmcMJarnnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}