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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0ec5f7edab7590648c7f842acd3df0bf90509a53dd4850a1f0df3f8ebf5e48c' 
  AND token = 'GPcte/wifqz/xWaAoiWDJlR2Ihc5DBbazge/+VuBEaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}