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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0739305ca767aed527fc978420a91e18557f9449d1064e69cab3c6ca5c768282' 
  AND token = 'veB8n8M/eQaFG5LDe6Yng26HgW1k3xlHR6Zdlc8ipJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}