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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de4081cc3640a261c7d32233291bf4af77d737c3f9770c1c9c9133c9bf6d8d8f' 
  AND token = 'Q307r2Md/U0CiyZHwzSr2cvPN1eec5o6RFv5d8No/eI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}