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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df461daf62b6ffca2ca884b482f3fd2f51f12b745c2f03c177af8cddb0ea7708' 
  AND token = 'I+dnxptvBpm4fxe3esye66et5o/kTBhprpOrFH3skwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}