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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b5f96104ffb0b6792b11c54c1245b54f90b222439cd2ec60d1348b7cb52e20c' 
  AND token = 'iripEiSIxRcw3Sx+YmbMA/OYYus8E56C4q2XrfFaSTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}